John Ioannidis discusses the potential effects on clinical research of a 2017 proposal to lower the default P value threshold for statistical significance from .05 to .005 as a means to reduce false-positive findings.
Climate skeptics, conspiracy theorists, and the anti-immunization movement are on the rise. At the same time, fraudulent research and issues with the replicability of scientific results prompt the question if science is still a reliable source for political decision-making.
Science, it turns out, is an excellent place to find such people. After all, the scientific method requires you to recognize when you’re wrong - to do so happily, in fact. The story of Daniel Bolnick, an evolutionary biologist who had the courage to recognize his mistake.
Modelling Science Trustworthiness Under Publish or Perish Pressure
Analysis suggesting that trustworthiness of published science in a given field is influenced by false positive rate, and pressures for positive results. We find decreasing available funding has negative consequences for resulting trustworthiness, and examine strategies to combat propagation of irreproducible science.